176 e-Letters

published between 2013 and 2016

  • Total and high molecular weight adiponectin are positively associated with incident atrial fibrillation by a follow-up study
    Tomoyuki Kawada

    I read with great interest the report by Macheret et al., (1) who conducted an 11-year prospective study in 3190 older adults, aged 65 years or older, without cardiovascular disease for monitoring incident atrial fibrillation (AF). The authors measured plasma total adiponectin, high molecular weight (HMW) adiponectin and amino-terminal pro-brain natriuretic peptide 1-76 (NT-proBNP1-76). There were 886 incident AF events,...

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  • Genomics in cardiology: new findings in old syndromes?
    Dilip Abraham

    Last year, in response to Priest and Ashley's paper on genomics in cardiology1, we urged close collaboration of congenital cardiologist and geneticist for some adults with congenital heart conditions, who had not been tested in childhood2. The converse is also pertinent. A recent case (23year old female) with chromosome 1p36 deletion* (previous PDA and VSD closure in childhood) presented at another hospital with TIA's;...

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  • Increasing professional and societal awareness of the uncertainty underpinning hypertrophic cardiomyopathy (HCM)
    Branavan Anandasundaram

    I read with great interest the above guidelines published for this rare inherited heart disorder. Over the past few years, much work has gone into elucidating possible risk factors and markers which can help predict sudden cardiac death in such patients. Namely, we have already established that myocardial fibrosis, age and certain mutations in cardiac genes are markers indicative of a higher risk of sudden cardiac death for t...

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  • Re:Correspondence: A not so typical pericardial effusion case
    Rick A. Nishimura

    To the Editor:

    We have read over and agree with the insightful comments of Lazaros at al. Our clinical vignette mainly focused on the hemodynamic abnormalities and post-pericardiocentesis diagnosis. Therefore, some of the clinical details had to be omitted for purposes of brevity. A pericardial rub was present during our patient's initial evaluation, and she later developed chest pain consistent with pericardi...

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  • Re:The key role of the right ventricle in the pathogenesis of acute pulmonary oedema
    David M. Viau

    We thank Drs. MacIver and Clark for their comments regarding the role of the right ventricle in the development of acute pulmonary edema. We agree that a relative mismatch in stroke volume from the right and left sides of the heart can contribute to alveolar congestion [1]. Although we did mention preload as an important contributor to development of hypertensive acute heart failure (AHF), we chose to simplify the dis...

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  • Plasma N-terminal-pro-brain natriuretic peptide as a useful biomarker for predicting all-cause death in patients with heart failure regardless of the levels of left ventricular ejection fraction
    Tomoyuki Kawada

    I read with great interest the report by Kang et al., (1) who conducted one-year prospective study in 1670 patients with heart failure (HF). The authors measured plasma N-terminal-pro-brain natriuretic peptide (NT-proBNP), and left ventricular ejection fraction (LVEF) was used for binary classification of HF. Although patients with keeping LVEF showed significantly lower NT-proBNP level than those with reduced LVEF, all-...

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  • Habitual chocolate consumption and risk of cardiovascular disease among healthy men and women: Pre-determined research or/ "made-to-order" research ?
    Rajiv Kumar

    As a part of a low-fat diet regular consumption of chocolate (containing plant sterols [PS] and cocoa flavanols [CF] ) improve cardiovascular health by lowering cholesterol and improving blood pressure [1]. Exact mechanism remains uncertain. Chocolates are a rich source of catechins, a protective molecule against heart diseases, cancer, and other medical conditions. Catechin content highest in dark, bitter chocolate and l...

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  • Misinterpretation risks with a superficial reading of a meta-analysis. Reply to the letter by Nairooz et al.
    Eliano P. Navarese

    Nairooz and Naidu [1] claim that definitions of complete and non- complete MV-PCI in our meta-analysis[2] (multivessel percutaneous coronary intervention) might have been missed or misinterpreted in one included study. As a matter of fact, CvLPRIT trial randomized STEMI (ST-elevation myocardial infarction) patients to either complete revascularization (including all N-IRAs [non-infarct related artery]) or IRA-only treatmen...

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  • Re:Ischaemic conditioning: paving the pathway to clinical translation
    Heerajnarain Bulluck

    We thank Iliodromitis and colleagues for their interest in our review article1. Providing a comprehensive account of the extensive literature in this field has been a very challenging task. We are aware of their previous work2 3 on the feasibility of ischaemic postconditioning (IPost) in acute coronary syndrome. Of note, this was a small study of 37 patients and only included a total of 6 patients with non-ST elevation myoc...

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  • Radiation exposure considerations relevant to using propofol for nurse-led sedation in cardiological practice
    Aaron Conway
    The authors should be congratulated for providing timely guidance about the use of propofol for nurse-led sedation in modern cardiological practice.[1] The broad scope of the article surely prevented presentation of a comprehensive set of recommendations. However, a particularly important issue for the nursing staff who would be involved, which was not addressed in this article, deserves focused attention. A recent study reported...
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