200 e-Letters

published between 2007 and 2010

  • Frailty: the great confounder, the great forgotten
    Roman Romero-Ortuno
    Corresponding author information: Name: Roman Surname: Romero-Ortuno Email: romeror@tcd.ie Affiliation: Department of Medicine for the Elderly, St James's Hospital, James's Street, Dublin 8, Ireland

    Frailty: the great confounder, the great forgotten

    To the editor: Ryan, Steen, Seifer, et al. [1] present the results of SAFE PACE-2, which are at odds with SAFE PACE-1 [2]. The authors discuss that this may be due to gre...

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  • Preoperative NTproBNP and Perioperative Major Cardiovascular Events in Noncardiac Surgery
    M. Adnan Nadir
    We read the paper by Choi et al with great interest. [1] Clearly NTproBNP (and CRP) appeared to predict perioperative major cardiovascular events (PCME) better than the Revised Cardiac Risk Index (RCRI). The most traditional way to depict that one predictor is better than other is to use the c-statistic or the area under the ROC curve (AUC). Although the abstract states that NTproBNP and CRP performed better than RCRI by ROC ana...
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  • To the Editor: Ryan et al.
    John W McEvoy

    To the Editor: Ryan et al. report on the efficacy of Dual Chamber pacemaker implantation in patients with cardio-inhibitory carotid sinus hypersensitivity (CICSH) and falls in SAFEPACE-2 (Syncope And Falls in the Elderly- Pacing And Carotid sinus Evaluation)[1]. This study had the potential to expand on the findings of SAFEPACE-1 [2] and address some of the weaknesses of the latter with a blinded, multicenter, and less se...

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  • Understanding myocardial deformation, ‘global systolic function’ and abnormal geometry.
    David H MacIver

    To the editor: I read with interest Dr Cramariuc and colleagues excellent article published in Heart.1 The study showed the presence of abnormal longitudinal left ventricular strain in patients with aortic stenosis and concentric left...

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  • ozone protective effect
    Peter M Joseph
    November 11, 2009 Editor, Heart British Medical Journal Dear Sir: I am writing to comment on the excellent article by Bhaskaran et al in Heart[1], and especially on the editorial by David Newby [2] that commented on this paper. In my opinion, Dr. Newby has missed the most important conclusion of the Bhaskaran paper. Dr. Newby’s editorial was focused mainly on the cardiac effects of fine particulate pollution, and included a...
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  • Inflamatory Biomarkers
    Marcio Spagnol
    Dear Sir, We enjoyed the recent paper in Heart by Rana et 1, but were concerned that the sample was composed of approximately 80% of individuals with intermediate or high-risk of having an event, which impaired the diagnostic and prognostic accuracy of the assessed test. The markers used reflect the biological state of elevated risk of an adverse outcome in the studied subjects that is secondary to the interaction of risk-factor...
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  • “Pro-healing” coronary stent before undeferrable major non-cardiac surgery.
    Federico Piscione

    We read with great interest the work by Luckie et al., recently published in this Journal. (1) It's known that for patients who suffer from infiltrative, obstructive or bleeding carcinomas, or for high rupture risk aneurismal disease, a prompt surgical procedure may represent “survival”, and that in case of revascularization requirement, currently available options, either bare-metal or drug-eluting stent or plain-old ba...

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  • Missing Data in Repeated Measures Study
    Hideaki Kaneda

    To the Editor: With great interest I read the article by Byrne et al. assessing antirestenotic efficacy of 3 different rapamycin-eluting stents with different coating strategies (biodegradable polymer, permanent polymer and polymer-free stents) at 2 time points after coronary stenting (6 to 8 months and 2 years) [1]. Although the authors suggested delayed late loss (the difference in in-stent late loss between 6 to 8 mont...

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  • Endothelial dysfunction and necrotic core plaques
    Scott W Murray

    To the Editor: We read with great interest the paper published by S Lavi et al [1] and feel that it is worthy of comment. We admire the foresight and technical expertise that has gone into creating this study, to try and prove a worthy concept. However, we do have an issue regarding the measurement of Necrotic Core in minimal plaques. The authors state that after selecting the appropriate frames "two independent investi...

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  • T2 Weighted Magnetic Resonance Imaging to Assess Myocardial Oedema In Ischemic Heart Disease
    Steffen Bohl

    To the Editor:

    We read with interest the comprehensive review article on T2-weighted (T2w) cardiovascular magnetic resonance imaging (CMR) by Edwards, Routledge and Steeds (1). We wish to make one comment for the sake of clarity and also to bring to the reader’s attention important new data, which have become available in the meantime and light up some of the issues raised by the authors. The authors cite one...

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