eLetters

174 e-Letters

published between 2001 and 2004

  • Authors' Reply: Smoking and inflammation
    Dimitris Tousoulis

    Dear Editor

    In a response letter Cope et al. stated that smoking or the amount of tobacco consumed did not influence the biochemical risk factors for coronary artery disease such as cholesterol and HDL, but increased many of the cellular factors which we have reported in the recent review article as contributors to the inflammatory response and to the formation and instability of the atheromatous plaque.[1]...

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  • Evidence-based treatment of tuberculous pericarditis
    Bongani M Mayosi

    Dear Editor

    I would like to point out that Maisch and Ristic's recomendations [1] on the duration of treatment and the use of adjuvant steroids in tuberculous pericarditis are not consistent with the best available evidence. They advise treatment for '9-12 months' with anti-tuberculous drugs. In a recent systematic review of clinical trials of antituberculous chemotherapy in patients with tuberculous pericarditis,...

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  • Low pressure giant pulmonary artery aneurysms: a report of two cases
    Gian M. Novaro

    Dear Editor

    We read with great interest the report discussing the management strategies of low pressure giant pulmonary artery aneurysms.[1] As these cases are uncommon, the natural history ill defined, and management controversial, we wish to further contribute to the literature, discussing two adult cases of giant low pressure pulmonary artery aneurysms, one presenting with and the other without symptoms.

    ...

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  • Cholinergic stimulation in chronic heart failure: modifiyng predictors of risk
    Antonio C.L. Nobrega

    Dear Editor

    The article by Androne et al.[1] describing the improvement in heart rate recovery after maximal exercise in patients with chronic heart failure when treated with pyridostigmine, supports the recent concept that cholinergic stimulation may have a protective role in cardiovascular disease.[2] We have prompted to investigate this possibility, since depressed heart rate variability[3] and baroref...

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  • Newcastle Heart Project shows ethnic variations in chest pain site
    Raj S Bhopal

    Dear Editor

    Barakat and colleagues' observations are clinically important. Our work on the performance of the Rose angina questionnaire in a multi- ethnic study of a community based sample of 1509 adults from European, Indian, Pakistani and Bangladeshi ethnic groups corroborates and complements, their observations.[1]

    European men and women mostly reported chest pain in Rose Questionnaire (definite angina c...

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  • Response to Cheung
    Bosi Giuliano

    Dear Editor

    We thank Dr Cheung for the interesting observations [1]concerning our paper.[2]

    They suggest - on the basis of their study,[3] that an arterial dysfunction (probably due to iron overload) could contribute to the pathogenesis of the so-called “Thalassemic cardiomyopathy” causing an increase of arterial stiffness and, consequently, an increase of the pulsatile pressure if the ventricular systoli...

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  • National Institute of Clinical Excellence
    J Gunn

    Dear Editor

    On 24 June the National Institute of Clinical Excellence (NICE) issued their Appraisal consultation document: coronary artery stents.[1] With the proviso that ‘the decision to use a bare metal stent or drug-eluting stent (DES) will depend on the anatomy of the target vessel for stenting and the severity of the disease’ (presumably reflecting issues of deliverability of the stent platforms on offer), t...

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  • PAMPAS Study : more power to the arm for transradial access
    Ian R Hall

    Dear Editor

    We were interested to read the recent scientific letter from Pollard et al published in Heart.[1]

    The authors evaluated the safety of a protocol for earlier sit up and mobilisation after routine transfemoral cardiac catheterisation in contemporary practice. Patients were randomised to be mobilised after 2½ hours or 4½ hours bed rest. The authors report that a significant reduction in...

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  • Re: Apical thrombus associated with left ventricular apical ballooning
    Tetsuya Sato

    Dear Editor

    I read the article by Barrera-Ramirez et al. with interest and have some comments.

    I think this case is an extensive myocardial stunning induced by emotional stress. Some stunning occured with emotional stress, cerebrovascular attack, and surgery. Symathetic denervation is involved in such cases. Prolonged T wave inversion would indicate the change in repolarization related to the sympathetic...

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  • Smoking and thrombotic mechanisms
    Graham F. Cope

    Dear Editor

    We read the review paper by Tousoulis et al. with great interest. We applaud their thoroughness in describing the molecular and cellular mechanisms involved in the inflammatory mechanisms and haemostatic factors leading to coronary atherosclerosis. They also describe the role of chronic infection in this process.[1] However, they omit an important factor that is common to the majority of patients su...

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