Blood urea nitrogen and serum creatinine are imperfect markers of kidney function because
they are influenced by many renal and nonrenal factors independent of kidney function. A …

BACKGROUND The kidney performs a multitude of essential functions to maintain
homeostasis. In clinical medicine, glomerular filtration rate (GFR) provides the best index of …

Blood urea nitrogen (BUN) and serum creatinine (SCr) are not very sensitive and specific
markers of kidney function in acute kidney injury (AKI) as they are influenced by many renal …

Abstract Background. Plasma cystatin C (pCysC) has been proposed as an alternative to
plasma creatinine (pCr) as a measure of renal function. We compared the detection of …

Glomerular filtration rate (GFR) is routinely used as a surrogate endpoint for the
development of investigational drugs in clinical trials. GFR and staging of chronic kidney …

Introduction To evaluate the utility of urinary cystatin C (uCysC) as a diagnostic marker of
acute kidney injury (AKI) and sepsis, and predictor of mortality in critically ill patients …

Renal transplantation ensures distinct advantages for patients with end-stage kidney
disease. However, in some cases early complications can lead to allograft dysfunction and …

Purpose To describe current knowledge on the epidemiology of cardiac surgery-associated
acute kidney injury (CSA-AKI) and to formulate recommendations for clinical practice and a …

Acute kidney injury (AKI) is a common problem in both the inpatient and outpatient setting
and often results from drug toxicities. Traditional methods of identifying AKI, through …

Background The accurate early diagnosis of acute kidney injury (AKI) in patients with acute
heart failure (AHF) is an unmet clinical need. Cystatin C might improve the early detection of …