PT - JOURNAL ARTICLE AU - Teun van der Bom AU - Barbara JM Mulder AU - Folkert J Meijboom AU - Arie PJ van Dijk AU - Petronella G Pieper AU - Hubert W Vliegen AU - Thelma C Konings AU - Aeilko H Zwinderman AU - Berto J Bouma TI - Contemporary survival of adults with congenital heart disease AID - 10.1136/heartjnl-2015-308144 DP - 2015 Dec 15 TA - Heart PG - 1989--1995 VI - 101 IP - 24 4099 - http://heart.bmj.com/content/101/24/1989.short 4100 - http://heart.bmj.com/content/101/24/1989.full SO - Heart2015 Dec 15; 101 AB - Background Survival data that are applicable to the current population of adults with congenital heart disease (CHD) are not available.Objectives Using an alternative survival analysis with age as the primary time scale, we assessed the contemporary survival of adult patients with CHD.Methods Survival was assessed using prospective data of the national registry of adult patients with CHD of the Netherlands. Survival was stratified by severity and lesion, and compared with a standardised general population.Results Mean age at inclusion was 37 years, and 49% of the study population was male. During a cumulative prospective follow-up of 90 270 patient-years in 14 327 patients, 535 deaths occurred. Median survival was 53.4 (95% CI 49.9 to 60.7), 75.4 (95% CI 72.9 to 79.1) and 84.1 (95% CI 81.9 to 87.0) years for patients with severe, moderate and mild lesions, respectively. Survival of most patients with mild lesions did not differ from the general population, while, as expected, survival of patients with severe and moderate lesions was substantially lower (<0.001).Conclusions The present study gives insight in the contemporary survival of adults with CHD. This may aid patient counselling, timing of interventions and future research.