RT Journal Article SR Electronic T1 Coronary anatomy in Turner syndrome versus patients with isolated bicuspid aortic valves JF Heart JO Heart FD BMJ Publishing Group Ltd and British Cardiovascular Society SP 701 OP 707 DO 10.1136/heartjnl-2018-313724 VO 105 IS 9 A1 Wilke M C Koenraadt A1 Hans-Marc J Siebelink A1 Margot M Bartelings A1 Martin J Schalij A1 Maureen J van der Vlugt A1 Annemien E van den Bosch A1 Ricardo P J Budde A1 Jolien W Roos-Hesselink A1 Anthonie L Duijnhouwer A1 Allard T van den Hoven A1 Marco C DeRuiter A1 Monique R M Jongbloed YR 2019 UL http://heart.bmj.com/content/105/9/701.abstract AB Objective Variations in coronary anatomy, like absent left main stem and left dominant coronary system, have been described in patients with Turner syndrome (TS) and in patients with bicuspid aortic valves (BAV). It is unknown whether coronary variations in TS are related to BAV and to specific BAV subtypes.Aim To compare coronary anatomy in patients with TS with/without BAV versus isolated BAV and to study BAV morphology subtypes in these groups.Methods Coronary anatomy and BAV morphology were studied in 86 patients with TS (20 TS-BAV, 66 TS-tricuspid aortic valve) and 86 patients with isolated BAV (37±13 years vs 42±15 years, respectively) by CT.Results There was no significant difference in coronary dominance between patients with TS with and without BAV (25% vs 21%, p=0.933). BAVs with fusion of right and left coronary leaflets (RL BAV) without raphe showed a high prevalence of left coronary dominance in both TS-BAV and isolated BAV (both 38%). Absent left main stem was more often seen in TS-BAV as compared with isolated BAV (10% vs 0%). All patients with TS-BAV with absent left main stem had RL BAV without raphe.Conclusion The equal distribution of left dominance in RL BAV without raphe in TS-BAV and isolated BAV suggests that presence of left dominance is a feature of BAVs without raphe, independent of TS. Both TS and RL BAV without raphe seem independently associated with absent left main stems. Awareness of the higher incidence of particularly absent left main stems is important to avoid complications during hypothermic perfusion.