TY - JOUR T1 - Are biventricular and biatrial function truly preserved after arterial switch operation? JF - Heart JO - Heart SP - 1609 LP - 1610 DO - 10.1136/heartjnl-2021-319820 VL - 107 IS - 20 AU - Ellen Ostenfeld AU - Marcus Carlsson Y1 - 2021/10/01 UR - http://heart.bmj.com/content/107/20/1609.abstract N2 - Arterial switch operation is currently the standard procedure when correcting for transposition of the great arteries (TGA) with a good longevity of the intervention.1 While aortic and coronary artery complications as well as mortality are low, right-sided lesions such as right ventricular (RV) outflow and neopulmonary valve dysfunction may occur and require reintervention.2 Patients undergoing cardiac reinterventions in childhood are more likely to have residual lesions and have a higher risk of valvular and ventricular dysfunction as well as arrhythmia.3 In TGA, left ventricular (LV) function is reported normal at long-term follow-up,4 5 but RV dysfunction is present at mid-term after arterial switch operation.6 Systemic ventricular function has been suggested as a prognostic marker of outcome in TGA after atrial switch and in congenital corrected TGA.7 Even if echocardiography is the first-line imaging modality for cardiovascular evaluation of patients with congenital heart disease, cardiac magnetic resonance (CMR) is considered gold standard for ventricular and atrial volumes and function owing to high accuracy, precision and reproducibility.8 As most studies of patients with TGA and arterial switch operation are small cohorts presenting either on a ventricular or atrial functional results, whole heart assessment including all four cardiac chambers in a comprehensive manner has been lacking. A larger population of patients with TGA and arterial switch operation also allows a meaningful investigation of whether any ventricular and atrial functional alterations could be caused by differences in simple and complex TGA morphology or by usual and … ER -