RT Journal Article SR Electronic T1 Changes in aortic valve replacement procedures in Denmark from 2008 to 2020 JF Heart JO Heart FD BMJ Publishing Group Ltd and British Cardiovascular Society SP 557 OP 563 DO 10.1136/heartjnl-2022-321594 VO 109 IS 7 A1 Peter Laursen Graversen A1 Jawad Haider Butt A1 Lauge Østergaard A1 Andreas Dalsgaard Jensen A1 Peder Emil Warming A1 Jarl Emanuel Strange A1 Christian H Møller A1 Morten Schou A1 Ole De Backer A1 Lars Køber A1 Emil Loldrup Fosbøl YR 2023 UL http://heart.bmj.com/content/109/7/557.abstract AB Introduction Since 2007, transcatheter aortic valve implantation (TAVI) has emerged as another treatment strategy for severe symptomatic aortic stenosis (AS) compared with surgical aortic valve replacement (SAVR). The objectives were to compare annual rates of aortic valve replacement (AVR) procedures performed in Denmark in the era of TAVI and to assess proportion of AVRs stratified by age with use of age recommendations presented in current guidelines.Methods Using Danish nationwide registries, we identified first-time AVRs between 2008 and 2020. Patients who were not diagnosed with AS prior to AVR were excludedResults The rate of AVRs increased by 39% per million inhabitants from 2008 to 2020. TAVI has steadily increased since 2008, accounting for 64.2% of all AVRs and 72.5% of isolated AVRs by 2020. Number of isolated SAVRs decreased from 2014 and onwards. The proportion of TAVI increased significantly across age groups (<75 and ≥75 years of age, ptrend<0.001), and TAVI accounted for 91.5% of isolated AVR procedures in elderly patients (aged ≥75 years). Length of hospital stay were significantly reduced for all AVRs during the study period (ptrend all<0.001).Conclusions The number of AVRs increased from 2008 to 2020 due to adaptation of TAVI, which represented 2/3 of AVRs and more than 70% of isolated AVRs. In elderly patients, the increased use of AVR procedures was driven by TAVI, in agreement with the age recommendations in current guidelines; however, TAVI was used more frequently in patients aged <75 years, accompanied by a flattening use of SAVR.No data are available.