PT - JOURNAL ARTICLE AU - Bopp, P AU - Fournet, P C AU - Moret, P R AU - Duchosal, P W TI - Determination of regional and central circulation times by the ascorbate dilution method. AID - 10.1136/hrt.32.6.754 DP - 1970 Nov 01 TA - British Heart Journal PG - 754--757 VI - 32 IP - 6 4099 - http://heart.bmj.com/content/32/6/754.short 4100 - http://heart.bmj.com/content/32/6/754.full SO - Heart1970 Nov 01; 32 AB - The usefulness of the ascorbate dilution method in demonstrating intracardiac shunts and valvular incompetence is known. The ascorbate technique can also be applied to the determination of the transit time of regional vascular beds such as the coronary and the renal systems. Furthermore, the determination of central circulation times may be helpful in the diagnosis of caval obstruction. The method is safe, simple, inexpensive, and reliable.