RT Journal Article SR Electronic T1 Acute massive pulmonary embolism JF British Heart Journal JO Heart FD BMJ Publishing Group Ltd and British Cardiovascular Society SP 518 OP 523 DO 10.1136/hrt.32.4.518 VO 32 IS 4 A1 G. A. H. Miller A1 G. C. Sutton YR 1970 UL http://heart.bmj.com/content/32/4/518.abstract AB Twenty-three patients are reported in whom a diagnosis of acute massive pulmonary embolism was confirmed by pulmonary arteriography. All patients had a history of less than 48 hours' duration and only two had previous cardiorespiratory disease. In such patients the haemodynamic abnormalities determined at catheterization are due to pulmonary embolism as an isolated disturbance. These abnormalities include an only moderate degree of pulmonary hypertension (PA systolic pressure 38.4±6.8 mm. Hg), right ventricular `failure' (RVED 11.5±4.9 mm. Hg), arterial oxygen desaturation (86.4±11.2%) and a wide arteriovenous oxygen difference (8.1±1.8 ml./100 ml.), and low cardiac output. These haemodynamic abnormalities find their expression in the presentation and the clinical, electrocardiographic, and radiological findings which are described.