PT  - JOURNAL ARTICLE
AU  - J S Birkhead
AU  - E M Vaughan Williams
TI  - Dual effect of disopyramide on atrial and atrioventricular conduction and refractory periods.
AID  - 10.1136/hrt.39.6.657
DP  - 1977 Jun 01
TA  - British Heart Journal
PG  - 657--660
VI  - 39
IP  - 6
4099  - http://heart.bmj.com/content/39/6/657.short
4100  - http://heart.bmj.com/content/39/6/657.full
SO  - Heart1977 Jun 01; 39
AB  - Disopyramide has been shown in conditions of cholinergic blockade to have a depressant effect upon sinus node automaticity and the atrial refractoriness. It also prolongs atrioventricular conduction and increases atrioventricular refractoriness. These effects may often be masked in vivo by the anticholinergic effects of the drug.