RT Journal Article
SR Electronic
T1 Relations between ejection fraction and ventricular volume, and their alteration by chronic beta-blockade.
JF British Heart Journal
JO Heart
FD BMJ Publishing Group Ltd and British Cardiovascular Society
SP 17
OP 22
DO 10.1136/hrt.46.1.17
VO 46
IS 1
A1 P L Kerkhof
A1 J Baan
A1 B Buis
A1 A C Arntzenius
YR 1981
UL http://heart.bmj.com/content/46/1/17.abstract
AB This study describes the newly discovered relation between ejection fraction and end-systolic volume index (ESVI) of the left ventricle as obtained by angiography at the time of cardiac catheterisation. Linear regression analysis shows that ejection fraction (%)=82.0-0.62 ESVI (ml/m2) but the correlation for patients receiving beta-adrenergic blocking drugs is significantly lower compared with the untreated group. Non-linear analysis, applied to cover also the asymptotic range for ejection fraction less than 20%, shows similar results. The good relation between the two indices indicates that the index ejection fraction may derive its clinical importance directly from the more fundamental index end-systolic volume index by virtue of the operation of the beta-adrenergic system on the heart.