RT Journal Article SR Electronic T1 Angiographic and risk factor characteristics of subjects with early onset ischaemic heart disease. JF British Heart Journal JO Heart FD BMJ Publishing Group Ltd and British Cardiovascular Society SP 325 OP 330 DO 10.1136/hrt.46.3.325 VO 46 IS 3 A1 S Nitter-Hauge A1 J Erikssen A1 E Thaulow A1 K Vatne YR 1981 UL http://heart.bmj.com/content/46/3/325.abstract AB Sixty-six consecutive patients less than 40 years of age with angiographically documented coronary artery disease and coronary heart disease took part in a study aimed at (1) identifying the presence of factors which might explain the premature onset of ischaemic heart disease, and (2) assessing the distribution and severity of the coronary artery lesions. For comparisons we have used a study of risk factors in 1832 men defined as "normals" according to a recent comprehensive examination. The findings show that the typical early onset coronary heart disease case is an overweight, heavily smoking male "blue collar" worker, with high serum levels, a marginally raised blood pressure, and a high prevalence of coronary heart disease among first degree relatives. Coronary angiography showed a preponderance of one vessel disease. In particular, left anterior descending artery lesions were common, which might have contributed to the early manifestation of disease.