PT - JOURNAL ARTICLE AU - Behan, W M AU - Aitchison, M AU - Behan, P O TI - Pathogenesis of heart block in a fatal case of dermatomyositis. AID - 10.1136/hrt.56.5.479 DP - 1986 Nov 01 TA - British Heart Journal PG - 479--482 VI - 56 IP - 5 4099 - http://heart.bmj.com/content/56/5/479.short 4100 - http://heart.bmj.com/content/56/5/479.full SO - Heart1986 Nov 01; 56 AB - Approximately 70% of patients with dermatomyositis have evidence of cardiac damage; in one third of cases this affects principally or solely the conduction tissue. In infants similar histological lesions have been associated with a maternal autoantibody, anti-Ro, that crosses the placenta and produces congenital heart block. Anti-Ro antibody was detected in a fatal case of dermatomyositis with lesions of the conduction system.