RT Journal Article SR Electronic T1 Idiopathic infantile arterial calcification in two siblings: failure of treatment with diphosphonate. JF British Heart Journal JO Heart FD BMJ Publishing Group Ltd and British Cardiovascular Society SP 156 OP 159 DO 10.1136/hrt.64.2.156 VO 64 IS 2 A1 G Stuart A1 C Wren A1 H Bain YR 1990 UL http://heart.bmj.com/content/64/2/156.abstract AB Two siblings with idiopathic infantile arterial calcification are reported. The fetal and postnatal echocardiographic features were a large pericardial effusion, thickened pulmonary and aortic valves, poor pulsation of the descending aorta, and calcification of the great vessels. In one patient calcification was first detected at 33 weeks' gestation. Despite treatment with disodium etidronate both children died.