PT - JOURNAL ARTICLE AU - Phadke, K V AU - Phillips, R A AU - Clarke, D T AU - Jones, M AU - Naish, P AU - Carson, P TI - Anticardiolipin antibodies in ischaemic heart disease: marker or myth? AID - 10.1136/hrt.69.5.391 DP - 1993 May 01 TA - British Heart Journal PG - 391--394 VI - 69 IP - 5 4099 - http://heart.bmj.com/content/69/5/391.short 4100 - http://heart.bmj.com/content/69/5/391.full SO - Heart1993 May 01; 69 AB - OBJECTIVES--To assess the incidence and significance of anticardiolipin antibodies after myocardial infarction and in unstable angina. DESIGN--A prospective study of all patients under 60 admitted to the coronary care unit over a 12 month period with a diagnosis of acute myocardial infarction who were followed up for a further 12 months. Patients admitted with unstable angina were similarly assessed but not followed up. Anticardiolipin antibody concentrations were compared with those of age matched controls. SETTING--A district general hospital. PATIENTS--307 patients with acute myocardial infarction and 160 patients with unstable angina. RESULTS--Anticardiolipin antibody concentrations in the two patient groups did not differ significantly from those in the control groups. Antibody concentrations were not related to a history of angina or myocardial infarction nor were they related to subsequent cardiovascular complications. CONCLUSION--This study shows no significant association between anticardiolipin antibody concentrations and either myocardial infarction or unstable angina.