RT Journal Article
SR Electronic
T1 Anticardiolipin antibodies in ischaemic heart disease: marker or myth?
JF British Heart Journal
JO Heart
FD BMJ Publishing Group Ltd and British Cardiovascular Society
SP 391
OP 394
DO 10.1136/hrt.69.5.391
VO 69
IS 5
A1 Phadke, K V
A1 Phillips, R A
A1 Clarke, D T
A1 Jones, M
A1 Naish, P
A1 Carson, P
YR 1993
UL http://heart.bmj.com/content/69/5/391.abstract
AB OBJECTIVES--To assess the incidence and significance of anticardiolipin antibodies after myocardial infarction and in unstable angina. DESIGN--A prospective study of all patients under 60 admitted to the coronary care unit over a 12 month period with a diagnosis of acute myocardial infarction who were followed up for a further 12 months. Patients admitted with unstable angina were similarly assessed but not followed up. Anticardiolipin antibody concentrations were compared with those of age matched controls. SETTING--A district general hospital. PATIENTS--307 patients with acute myocardial infarction and 160 patients with unstable angina. RESULTS--Anticardiolipin antibody concentrations in the two patient groups did not differ significantly from those in the control groups. Antibody concentrations were not related to a history of angina or myocardial infarction nor were they related to subsequent cardiovascular complications. CONCLUSION--This study shows no significant association between anticardiolipin antibody concentrations and either myocardial infarction or unstable angina.