PT - JOURNAL ARTICLE AU - G Iglesias Cubero AU - J J Rodriguez Reguero AU - J M Rojo Ortega TI - Restrictive cardiomyopathy caused by chloroquine. AID - 10.1136/hrt.69.5.451 DP - 1993 May 01 TA - British Heart Journal PG - 451--452 VI - 69 IP - 5 4099 - http://heart.bmj.com/content/69/5/451.short 4100 - http://heart.bmj.com/content/69/5/451.full SO - Heart1993 May 01; 69 AB - A 59 year old white woman who had been treated with chloroquine phosphate for 25 years presented with signs of congestive heart failure and was diagnosed as having restrictive cardiomyopathy by non-invasive methods. Electron microscopy of a biopsy specimen of skeletal muscle showed lesions compatible with chloroquine myopathy. The patient died five weeks after presentation. Electron microscopy of heart tissue showed similar lesions to those of the skeletal muscle.