RT Journal Article SR Electronic T1 Histoplasma endocarditis on a stenosed aortic valve presenting as dysphagia and weight loss. JF British Heart Journal JO Heart FD BMJ Publishing Group Ltd and British Cardiovascular Society SP 565 OP 567 DO 10.1136/hrt.70.6.565 VO 70 IS 6 A1 P T Wilmshurst A1 G E Venn A1 S J Eykyn YR 1993 UL http://heart.bmj.com/content/70/6/565.abstract AB A 40-year-old man with aortic stenosis and disseminated histoplasmosis did not respond to treatment with itraconazole. Though there was no haemodynamic deterioration, valvar regurgitation, or embolic phenomena a presumptive diagnosis of infective endocarditis was made. This was confirmed at aortic valve replacement. Antifungal treatment was continued for 18 months after valve replacement and serological tests for Histoplasma became progressively more negative during a three year follow up.