RT Journal Article
SR Electronic
T1 New concepts for interpretation of intracoronary velocity and pressure tracings.
JF British Heart Journal
JO Heart
FD BMJ Publishing Group Ltd and British Cardiovascular Society
SP 485
OP 492
DO 10.1136/hrt.74.5.485
VO 74
IS 5
A1 Di Mario, C.
A1 Gil, R.
A1 Sunamura, M.
A1 Serruys, P. W.
YR 1995
UL http://heart.bmj.com/content/74/5/485.abstract
AB The development of quantitative angiography and the introduction of new imaging techniques cannot replace functional methods of assessing the severity of stenosis. Measurement of transstenotic pressure gradient and poststenotic flow velocity using miniaturised sensors with guidewire technology offers an alternative to the conventional non-invasive methods that is immediately applicable in the catheterisation laboratory during interventional procedures. The complexity of the coronary circulation, however, makes it difficult to establish simple cut-off criteria to identify the presence of a flow-limiting stenosis. For intermediate lesions or in the presence of variable haemodynamic conditions, the accuracy of the assessment can be improved by the application of more complex indices proposed and validated in the laboratory animals. Two of these indices are myocardial fractional flow reserve and the slope of the instantaneous relation between pressure or pressure gradient and flow velocity.