RT Journal Article
SR Electronic
T1 Three year continuous abstinence in a smoking cessation study using the nicotine transdermal patch
JF Heart
JO Heart
FD BMJ Publishing Group Ltd and British Cardiovascular Society
SP 617
OP 618
DO 10.1136/hrt.78.6.617
VO 78
IS 6
A1 Robyn L Richmond
A1 Linda Kehoe
A1 Abilio Cesar de Almeida Neto
YR 1997
UL http://heart.bmj.com/content/78/6/617.abstract
AB A total of 305 subjects from Sydney were randomly allocated to receive either an active (24 hour transdermal nicotine patch over a 10 week course) or placebo nicotine patch. All subjects participated in a multicomponent cognitive–behavioural smoking cessation programme over five weeks in two-hour group sessions. The continuous abstinence rates at three years (validated by expired carbon monoxide) were 13.8% for the active group and 5.2% for placebo group (p = 0.011). The active nicotine patch with behavioural therapy achieved more than double the abstinence rates early in treatment compared with placebo and this difference was maintained throughout the three year follow up.