RT Journal Article
SR Electronic
T1 Brugada syndrome associated with an autonomic disorder
JF Heart
JO Heart
FD BMJ Publishing Group Ltd and British Cardiovascular Society
SP 194
OP 196
DO 10.1136/hrt.80.2.194
VO 80
IS 2
A1 M Nomura
A1 T Nada
A1 J Endo
A1 Y Kondo
A1 M Yukinaka
A1 K Saito
A1 S Ito
A1 H Mori
A1 Y Nakaya
A1 H Shinomiya
YR 1998
UL http://heart.bmj.com/content/80/2/194.abstract
AB A 44 year old man with Brugada syndrome and ventricular fibrillation had an autonomic disorder, shown by spectral analysis of heart rate variability and 123I-MIBG myocardial scintigraphy. Periodic variation of the ST segments was detected by Holter ECG. Increased high frequency power (0.15–0.40 Hz), an index of parasympathetic nerve activity, was observed just before ST segment elevation. In addition, local dysfunction of sympathetic nerves in the left ventricle was detected by 123I-MIBG myocardial scintigraphy. Unbalanced autonomic nerve function plays an important role in inducing Brugada-type ECG signs.