RT Journal Article
SR Electronic
T1 Multivessel coronary thrombosis, acute myocardial infarction, and no reflow in a patient with essential thrombocythaemia
JF Heart
JO Heart
FD BMJ Publishing Group Ltd and British Cardiovascular Society
SP e10
OP e10
DO 10.1136/heart.83.6.e10
VO 83
IS 6
A1 H Terada
A1 H Satoh
A1 A Uehara
YR 2000
UL http://heart.bmj.com/content/83/6/e10.abstract
AB Essential thrombocythaemia (ET) has been reported rarely to cause coronary thrombosis, but the management is still undefined. A 63 year old woman with multivessel coronary thrombosis, acute myocardial infarction (MI), and no reflow in reperfused coronary artery in association with ET is presented. The patient's platelet count was only moderately raised at the onset of MI, but peripheral blood smear and bone marrow evaluation revealed clumping giant platelets and numerous large hyperploid megakaryocytes. Long term prophylaxis with antiplatelet agents in patients with ET is recommended, even if the platelet count is not largely raised. Cytoreductive treatment may also be effective for secondary prevention when thrombotic complications occur.