RT Journal Article
SR Electronic
T1 Human coronary morphology after β radiation brachytherapy of in-stent restenosis
JF Heart
JO Heart
FD BMJ Publishing Group Ltd and British Cardiovascular Society
SP e32
OP e32
DO 10.1136/hrt.2003.026674
VO 90
IS 6
A1 Grewe, P H
A1 Deneke, T
A1 Hanefeld, C
A1 Müller, K-M
YR 2004
UL http://heart.bmj.com/content/90/6/e32.abstract
AB This case report discusses the human coronary morphological findings 18 hours after brachytherapy (β radiation) of an in-stent restenosis. Brachytherapy produced aseptic inflammation of the periadventitial connective tissue integrating the vasa vasorum in the acute phase. The stent neointima eight months after stenting and acutely 18 hours after radiation consisted of the same cellular components as human stent neointima of specimen not additionally treated with radiation. No evidence of necrosis or excessive fibrotic alterations of the arterial vessel wall have been found.