@article {Henneman1779, author = {M M Henneman and J D Schuijf and J W Jukema and H J Lamb and A de Roos and P Dibbets and M P Stokkel and E E van der Wall and J J Bax}, title = {Comprehensive cardiac assessment with multislice computed tomography: evaluation of left ventricular function and perfusion in addition to coronary anatomy in patients with previous myocardial infarction}, volume = {92}, number = {12}, pages = {1779--1783}, year = {2006}, doi = {10.1136/hrt.2006.087874}, publisher = {BMJ Publishing Group Ltd}, abstract = {Objective: To evaluate a comprehensive multislice computed tomography (MSCT) protocol in patients with previous infarction, including assessment of coronary artery stenoses, left ventricular (LV) function and perfusion. Patients and methods: 16-slice MSCT was performed in 21 patients with previous infarction; from the MSCT data, coronary artery stenoses, (regional and global) LV function and perfusion were assessed. Invasive coronary angiography and gated single-photon emission computed tomography (SPECT) served as the reference standards for coronary artery stenoses and LV function/perfusion, respectively. Results: 236 of 241 (98\%) coronary artery segments were interpretable on MSCT. The sensitivity and specificity for detection of stenoses were 91\% and 97\%. Pearson{\textquoteright}s correlation showed excellent agreement for assessment of LV ejection fraction between MSCT and SPECT (49 (13)\% v 53 (12)\%, respectively, r  =  0.85). Agreement for assessment of regional wall motion was excellent (92\%, κ  =  0.77). In 68 of 73 (93\%) segments, MSCT correctly identified a perfusion defect as compared with SPECT, whereas the absence of perfusion defects was correctly detected in 277 of 284 (98\%) segments. Conclusions: MSCT permits accurate, non-invasive assessment of coronary artery stenoses, LV function and perfusion in patients with previous infarction. All parameters can be assessed from a single dataset.}, issn = {1355-6037}, URL = {https://heart.bmj.com/content/92/12/1779}, eprint = {https://heart.bmj.com/content/92/12/1779.full.pdf}, journal = {Heart} }