PT - JOURNAL ARTICLE AU - G A Lanza TI - Cardiac syndrome X: a critical overview and future perspectives AID - 10.1136/hrt.2005.067330 DP - 2007 Feb 01 TA - Heart PG - 159--166 VI - 93 IP - 2 4099 - http://heart.bmj.com/content/93/2/159.short 4100 - http://heart.bmj.com/content/93/2/159.full SO - Heart2007 Feb 01; 93 AB - The classic definition of cardiac syndrome X (CSX) seems inadequate both for clinical and research purposes and should be replaced with one aimed at including a sufficiently homogeneous group of patients with the common plausible pathophysiological mechanism of coronary microvascular dysfunction. More specifically, CSX should be defined as a form of stable effort angina, which, according to careful diagnostic investigation, can reasonably be attributed to abnormalities in the coronary microvascular circulation.