RT Journal Article SR Electronic T1 Non-cardiac comorbidities in chronic heart failure JF Heart JO Heart FD BMJ Publishing Group Ltd and British Cardiovascular Society SP 665 OP 671 DO 10.1136/hrt.2005.068296 VO 93 IS 6 A1 Chim C Lang A1 Donna M Mancini YR 2007 UL http://heart.bmj.com/content/93/6/665.abstract AB Non-cardiac comorbidity complicates heart failure care and is prevalent in one form or another for the majority of elderly patients with heart failure. This wide range of comorbidities, which includes respiratory comorbidities, renal dysfunction, anaemia, arthritis, cognitive dysfunction and depression, contributes to the progression of the disease and may alter the response to treatment. Polypharmacy is inevitable in these patients. Cardiologists and other physicians caring for patients with chronic heart failure (CHF) need to be vigilant to comorbid conditions that may complicate the care of these patients. Future trials should focus on optimal strategies for the comprehensive management of the elderly patients with CHF with multiple comorbidities rather than the isolated effects of single drugs in younger patients with few or no comorbidities.