RT Journal Article SR Electronic T1 Mitral regurgitation in patients with aortic stenosis undergoing valve replacement JF Heart JO Heart FD BMJ Publishing Group Ltd and British Cardiovascular Society SP 9 OP 14 DO 10.1136/hrt.2009.165548 VO 96 IS 1 A1 P Unger A1 C Dedobbeleer A1 G Van Camp A1 D Plein A1 B Cosyns A1 P Lancellotti YR 2010 UL http://heart.bmj.com/content/96/1/9.abstract AB Mitral regurgitation is a frequent finding in patients with aortic stenosis scheduled for aortic valve replacement. Detection of mitral regurgitation in such patients has important implications, as it can independently affect functional status and prognosis. When mitral regurgitation is moderate to severe, a decision to operate on both valves should only be made following a careful clinical and echocardiographic assessment. Indeed, double-valve surgery increases perioperative and postoperative risks, and mitral regurgitation may improve spontaneously after isolated aortic valve replacement. Better understanding of the determinants of these changes appears particularly crucial in the light of recent advances in percutaneous aortic valve replacement.