RT Journal Article SR Electronic T1 e0463 Relationship between red cell distribution width and complication risk in patients with acute myocardial infarction JF Heart JO Heart FD BMJ Publishing Group Ltd and British Cardiovascular Society SP A144 OP A144 DO 10.1136/hrt.2010.208967.463 VO 96 IS Suppl 3 A1 Xu, Kaizu A1 Lin, Limin A1 Lin, Jinxiu A1 Zheng, Jiansheng A1 Cai, Dingnan YR 2010 UL http://heart.bmj.com/content/96/Suppl_3/A144.2.abstract AB Objective To investigate the relationship between red cell distribution width (RDW) level and risk of complication in acute myocardial infarction (AMI) patients; to compare the correlation of RDW with NT-proBNP, cTnI and hs-CRP. Methods From January 2006 to December 2009, 200 consecutive AMI patients admitted in cardiology department of affiliated hospital of putian university were enrolled. Patients were classified into complication group (n=145) or complication-free group (n=55) according to the presence or absence of new-onset symptomatic heart failure, arrhythmia or cardiac shock. Patients were divided into quartiles based on RDW value (≤12.8%, 12.9%–13.8%, 13.9%–14.7%, ≥14.8%, n=50 in each quartile), and OR of incident complication was calculated by using logistic regression. Correlation of RDW with NT-proBNP, cTnI and hs-CRP was compared by spearman rank correlation analysis. Results RDW levels in complication group was significantly higher than that in Complication-free group (14.5±0.97% vs 12.9±0.85%, p<0.05). RDW levels of AMI patients were positively associated with complication risk, after adjustment for estimated glomerular filtration rate, serum ferrum, left ventricular end-diastolic dimension, left ventricular ejection fraction, and plasma NT-proBNP, cTnI and hs-CRP levels, the highest RDW quartile entailed 1.96 times greater risk for complication than the lowest quartile (95% CI 1.34–2.79, P cTnI > hs-CRP (rs=0.31, 0.29 and 0.21 respectively, all p<0.05). Conclusion Higher RDW is closely associated with increased risk of AMI complication and elevated plasma NT-proBNP and cTnI level.