RT Journal Article SR Electronic T1 e0542 Transcatheter therapy of ventricular septal rupture in patients with acute myocardial infarction complicated by ventricular septal rupture JF Heart JO Heart FD BMJ Publishing Group Ltd and British Cardiovascular Society SP A168 OP A168 DO 10.1136/hrt.2010.208967.542 VO 96 IS Suppl 3 A1 Guang-Yi, WANG A1 Bao-Shi, HAN A1 Zhi-Feng, WANG A1 Hai-Jun, HOU A1 Yue, LI A1 Yu, WANG A1 Guang, ZHI A1 Yong, XU A1 Yun-Dai, CHEN YR 2010 UL http://heart.bmj.com/content/96/Suppl_3/A168.1.abstract AB Objective To explore the feasibility and clinical effects by transcatheter interventions used for the patient suffering acute myocardial infarction (AMI) complicating with ventricular septal rupture (VSR) postinfarction. Methods Between June 2005 and August 2009, Ventricular septal rupture (VSR) patients diagnosed with VSR underwent transcatheter closure aged 59–79 years old (mean 63.3±24.7). The occluders were released with the monitoring of transthoracic echocardiography (TTE) and X-ray fluoroscopy. Results 3 cases were successfully treated with transcatheter closure. The defect diameter was 11–28 (17±9.5) mm measured by TTE and the size of the occluder was 16–32 (21.3±7.6) mm. The occluder successful rate was 100%. The case success in 2 and a big VSR lead to die in 1. Conclusions VSR was showed by praecordial area auscultation, transthoracic echocardiography (TTE) and left ventricular angiography after AMI. The transcatheter closure of VSR postinfarction is alternative method in patients not suite for surgical closure. But the careful examination and preparation are need before transcatheter closure.