RT Journal Article SR Electronic T1 e0485 Clinic study of domestic tirofiban on TIMI Flow during facilitated PCI JF Heart JO Heart FD BMJ Publishing Group Ltd and British Cardiovascular Society SP A151 OP A151 DO 10.1136/hrt.2010.208967.485 VO 96 IS Suppl 3 A1 Guo Lai-jing A1 Hu Dayi A1 Huo Yong A1 Tang Qiang A1 Zhang Huiying A1 Xing Liying A1 Wang Zhi A1 Qu Huaqing A1 Shi Zhentao A1 Zhu Zhenzhong A1 Yan Do A1 Tang Qunzhong A1 Chen Xuezhi A1 Liu Xiumin YR 2010 UL http://heart.bmj.com/content/96/Suppl_3/A151.3.abstract AB Objective To assess Thrombolysis In Myocardial Infarction (TIMI) flow of the nation-produced tirofiban in patients with ST-segment elevation myocardial infarction (STEMI) during primary Percutaneous Coronary Intervention (PCI). Methods 120 patients with STEMI during primary PCI from Nov 2006 to June 2009 were divided into two groups, tirofiban+PCI group of 60 cases (51 males and 9 females) with mean age (60.11±10.96) years old, and the other primary PCI group of 60 cases (42 males and 18 females) with mean age (64.33±11.91) years. The TIMI flow before and after operation were observed in all cases angiographically. Results By using tirofiban before operation improved TIMI flow, a greater percentage of TIMI 1 grade flow was achieved in the tirofiban+PCI group compared with the primary PCI group before operation (13.3.8% vs 3.3%, p>0.05). There was no difference of TIMI 3 grade flow between the two groups after operation, TIMI 2 grade flow was lesser in tirofiban+PCI group (6.7% vs 3.4%, p>0.05).Reperfusion arrhythmia was lesser in tirofiban+PCI group (3.4% vs 6.7%). Conclusion Tirofiban may improve TIMI flow of the IRA in patients with STEMI during emergency PCI.