@article {Baron101, author = {Tomasz Baron and Kristina Hambraeus and Johan Sundstr{\"o}m and David Erlinge and Tomas Jernberg and Bertil Lindahl and TOTAL-AMI study group}, title = {Type 2 myocardial infarction in clinical practice}, volume = {101}, number = {2}, pages = {101--106}, year = {2015}, doi = {10.1136/heartjnl-2014-306093}, publisher = {BMJ Publishing Group Ltd}, abstract = {Objective We aimed to assess differences in incidence, clinical features, current treatment strategies and outcome in patients with type 2 vs. type 1 acute myocardial infarction (AMI). Methods and results All 20 138 hospitalisations in Sweden with a diagnosis of AMI registered during 2011 in the Swedish Web-system for Enhancement and Development of Evidence-based care in Heart disease Evaluated According to Recommended Therapies were classified into types 1{\textendash}5 in accordance with the universal definition of myocardial infarction (MI) from 2007. Type 1 AMI was present in 88.5\% of the cases while 7.1\% were classified as type 2 AMI. Higher age, female sex, comorbidities, impaired renal function, anaemia and smaller extent of myocardial necrosis characterised patients with type 2 AMI. While normal coronary arteries were more frequently seen (42.4\% vs. 7.4\%), an invasive treatment was less common, and antiplatelet medications were less prescribed in patients with type 2 AMI compared with type 1 AMI. The group with type 2 AMI had significantly higher crude 1-year mortality compared with the group with type 1 AMI (24.7\% vs. 13.5\%, p\<0.001). However, after adjustment, the HR for 1-year mortality in patients with type 2 AMI was 1.03 (95\% CI 0.86 to 1.23). Conclusions In this real-life study, 7.1\% of myocardial infarctions were classified as type 2 AMI. These patients were older, predominantly women and had more comorbidities. Invasive treatment strategies and cardioprotective medications were less used. Patients with type 2 AMI had higher crude mortality compared with type 1 patients with MI. However, after adjustment, the 1-year mortality was similar.}, issn = {1355-6037}, URL = {https://heart.bmj.com/content/101/2/101}, eprint = {https://heart.bmj.com/content/101/2/101.full.pdf}, journal = {Heart} }