PT - JOURNAL ARTICLE AU - Cheng, Andrew AU - Owens, David TI - Marfan syndrome, inherited aortopathies and exercise: What is the right answer? AID - 10.1136/heartjnl-2014-306440 DP - 2015 May 15 TA - Heart PG - 752--757 VI - 101 IP - 10 4099 - http://heart.bmj.com/content/101/10/752.short 4100 - http://heart.bmj.com/content/101/10/752.full SO - Heart2015 May 15; 101 AB - Exercise recommendations for those who have Marfan syndrome or other genetic predisposition for thoracic aortic disease remain controversial and at times ambiguous. There are no outcomes studies to help guide recommendations. In this review, we examine the guidelines regarding exercise and inherited aortic conditions, the theoretical reasoning and circumstantial evidence that support the guidelines, as well as the knowledge gaps that continue to exist.