Multivariate analysis of secondary preventive drugs prescribed at the time of hospital discharge
| Relative risk | 95% CI | p Value | |
|---|---|---|---|
| The model included sex, history of angina, myocardial infarction, stroke, or peripheral vascular disease, risk factors, type of institution, initial diagnosis, coronary angioplasty during the initial hospital stay, and for each class of drug, treatment with the same class before hospital admission; age and LVEF were also entered into the model as a categorical variables. | |||
| ACE, angiotensin converting enzyme; ACEI, angiotensin converting enzyme inhibitor; CI, confidence interval; LVEF, left ventricular ejection fraction; MI, myocardial infarction; PTCA, percutaneous transluminal coronary angioplasty; PVD, peripheral vascular disease. | |||
| Statins | |||
| Age (years) | |||
| 65–74 | 0.79 | 0.57 to 1.08 | 0.14 |
| 75+ | 0.33 | 0.21 to 0.50 | <0.001 |
| Statins before admission | 13.6 | 8.22 to 22.3 | <0.001 |
| Known hyperlipidaemia | 3.01 | 2.24 to 4.04 | <0.001 |
| PTCA | 1.70 | 1.28 to 2.27 | <0.001 |
| Admission to university hospital | 1.72 | 1.30 to 2.28 | <0.001 |
| Current smoking | 1.45 | 1.08 to 1.96 | <0.02 |
| Diabetes mellitus | 0.68 | 0.47 to 0.98 | <0.05 |
| Aspirin | |||
| PTCA | 2.87 | 1.82 to 4.52 | <0.001 |
| Admission for MI | 2.21 | 1.47 to 3.33 | <0.001 |
| Previous stroke | 0.23 | 0.12 to 0.44 | <0.001 |
| Aspirin before admission | 4.24 | 2.61 to 6.31 | <0.001 |
| Admission to university hospital | 2.02 | 1.32 to 3.09 | 0.001 |
| History of infarction | 0.57 | 0.36 to 0.90 | <0.02 |
| History of angina | 0.56 | 0.36 to 0.86 | <0.01 |
| Current smoking | 1.54 | 1.00 to 2.39 | 0.05 |
| β Blockers | |||
| Age (years) | |||
| 65–74 | 0.90 | 0.65 to 1.24 | NS |
| 75+ | 0.39 | 0.27 to 0.55 | <0.001 |
| PVD | 0.49 | 0.32 to 0.74 | <0.001 |
| PTCA | 1.46 | 1.11 to 1.92 | <0.01 |
| Admission for MI | 1.73 | 1.31 to 2.29 | <0.001 |
| β Blockers before admission | 6.01 | 4.19 to 8.61 | <0.001 |
| LVEF | |||
| 36–50% | 1.02 | 0.73 to 1.42 | NS |
| ≤35% | 0.28 | 0.17 to 0.44 | <0.001 |
| Not measured | 0.68 | 0.45 to 1.02 | NS |
| Sex (female) | 0.74 | 0.55 to 1.00 | 0.05 |
| ACE inhibitors | |||
| Admission for MI | 3.30 | 2.47 to 4.39 | <0.001 |
| ACEI before admission | 9.09 | 6.29 to 13.1 | <0.001 |
| Age (years) | |||
| 65–74 | 0.85 | 0.62 to 1.15 | NS |
| 75+ | 0.59 | 0.42 to 0.83 | <0.005 |
| Hypertension | 1.35 | 1.09 to 2.52 | <0.05 |
| LVEF | |||
| 36–50% | 3.23 | 2.37 to 4.41 | <0.001 |
| ≤35% | 7.27 | 4.36 to 12.1 | <0.001 |
| Not measured | 1.66 | 1.09 to 2.52 | <0.02 |