Ability of exercise test variables and age to discriminate for CHD in men with significant ST depression on exercise testing
| Exercise test variable | Percentage of subjects with CHD | p Value | Area under ROC curve | ||||
|---|---|---|---|---|---|---|---|
| First quintile | Second quintile | Third quintile | Fourth quintile | Fifth quintile | |||
| Data in parentheses indicate the range for each quintile. | |||||||
| *The time of the first normal ECG was available for only 87 subjects. For subjects for whom this variable was unknown, the time of the last abnormal ECG was at least 253 s. The mean (SD) interval between the time of the last abnormal and the first normal ECG was 59 (40) s. | |||||||
| Significant CHD | |||||||
| Usual symptoms during test | NS | ||||||
| Magnitude of ST depression | NS | 0.621 | |||||
| Time of first occurrence of ST depression (s) | 68.0 (318–710) | 96.0 (213–317) | 93.5 (161–212) | 100.0 (91–160) | 96.0 (<90) | NS | 0.795 |
| Time of last abnormal ECG in recovery (s) | 70.8 (<39.0) | 87.5 (39–240) | 96.0 (241–361) | 100.0 (362–500) | 100.0 (501–2603) | 0.045 | 0.837 |
| Time of first normal ECG in recovery (s)* | 70.6 (<57) | 78.9 (57–180) | 93.8 (181–360) | 100.0 (361–517) | 100.0 (518–1040) | NS | 0.814 |
| Duration of exercise test (s) | 72.0 (470–769) | 92.0 (376–469) | 92.0 (275–375) | 96.0 (210–274) | 100.0 (<210) | NS | 0.783 |
| Maximum heart rate (beats/min) | 72.0 (154–204) | 92.0 (144–153) | 95.8 (131–143) | 96.2 (123–13) | 95.8 (<122) | NS | 0.752 |
| Target heart rate (%) | 79.2 (100.6–127) | 87.5 (93.0–100.5) | 96.0 (85.0–92.9) | 96.0 (77.8–84.9) | 91.7 (<77.7) | NS | 0.677 |
| Increase in systolic blood pressure (mm Hg) | 88.0 (71–127) | 92.0 (49–70) | 88.0 (36–48) | 91.7 (25–35) | 92.0 (<25) | NS | 0.536 |
| Duke treadmill score | 72.7 (−4 to 3) | 88.5 (−7 to −5) | 93.8 (−11 to −8) | 95.2 (−14 to −12) | 100.0 (<−14) | NS | 0.793 |
| Age (years) | 83.3 (40.1–55.6) | 76.0 (55.6–63.4) | 95.8 (63.7–67.6) | 96.0 (67.6–70.7) | 100.0 (71.3–79.8) | NS | 0.733 |
| Prognostic coronary heart disease | |||||||
| Maximum heart rate (beats/min) | 40.0 | 52.0 | 70.8 | 50.0 | 70.8 | NS | 0.587 |
| Time of last abnormal ECG in recovery (s) | 33.3 | 50.0 | 64.0 | 66.7 | 70.8 | 0.024 | 0.663 |
| Time of first normal ECG in recovery (s) | 29.4 | 36.8 | 56.3 | 64.7 | 66.7 | NS | 0.670 |
| Duration of exercise test (s) | 32.0 | 52.0 | 44.0 | 76.0 | 79.2 | NS | 0.689 |
| Age (years) | 41.7 | 36.0 | 83.3 | 64.0 | 54.2 | NS | 0.600 |
| Duke treadmill score | 45.5 | 57.7 | 53.1 | 52.4 | 73.9 | NS | 0.600 |