Clinical and echocardiographic characteristics of women for whom data were unavailable before pregnancy but were collected at first presentation to St George’s Hospital
| Time of diagnosis | |||
|---|---|---|---|
| Before pregnancy | During or between pregnancies | After pregnancy | |
| Data are presented as mean (SD) and range. | |||
| %Vo2 max, maximal oxygen consumption during upright exercise testing; ABPR, abnormal blood pressure response to exercise; FHSCD, family history of sudden cardiac death; LVED, left ventricular end diastolic diameter; LVES, left ventricular end systolic diameter; LVOTG, left ventricular outflow tract gradient; MLVWT, maximal left ventricular wall thickness; NYHA, New York Heart Association. | |||
| Number of patients | 7 | 42 | 38 |
| Mean age at first pregnancy (years) | 24 (2) (19–27) | 26 (4) (18–33) | 24 (4) (16–36) |
| Mean age at review (years) | 29 (6) (29–44) | 33 (7) (31–41) | 34 (3) (27–53) |
| Angina | 2 (28.6%) | 10 (23.8%) | 10 (26.3%) |
| Dyspnoea (NYHA ⩾II) | 1 (14.5%) | 9 (21.4%) | 11 (28.9%) |
| Syncope | 0 (0%) | 4 (9.5%) | 5 (13.1%) |
| Palpitations | 1 (14.3%) | 7 (16.7%) | 6 (15.8%) |
| Ventricular tachycardia | 0 (0%) | 0 (0%) | 1 (2.6%) |
| Non-sustained ventricular tachycardia | 0 (0%) | 6 (14.3%) | 4 (10.5%) |
| Paroxysmal atrial fibrillation | 1 (14.3%) | 3 (7.1%) | 6 (15.8%) |
| Atrial fibrillation | 0 (0%) | 1 (2.4%) | 4 (10.5%) |
| FHSCD | 1 (14.3%) | 6 (14.3%) | 6 (15.8%) |
| ABPR | 1 (14.3%) | 6 (14.3%) | 3 (7.9%) |
| Mean %Vo2 max | 78 (16) (54–111) | 73 (9) (63–105) | 77 (12) (59–100) |
| Mean MLVWT (mm) | 21 (4) (15–26) | 23 (5) (15–31) | 19 (3) (14–30) |
| Mean LVED (mm) | 42 (3) (35–49) | 44 (4) (30–49) | 46 (5) (34–54) |
| Mean LVES (mm) | 29 (3) (21–34) | 28 (5) (16–41) | 30 (6) (17–42) |
| Mean fractional shortening (%) | 32 (7) (29–47) | 36 (6) (28–52) | 35 (4) (23–54) |
| Mean LVOTG (mmHg) | 25 (5) (1–39) | 21 (4) (1–36) | 22 (5) (1–112) |
| Mean left atrium (mm) | 43 (2) (33–49) | 45 (4) (36–67) | 46 (4) (32–63) |
| Implantable cardioverter-defibrillator | 0 (0%) | 0 (0%) | 0 (0%) |
| Myectomy | 0 (0%) | 1 (2.4%) | 0 (0%) |
| Pacemaker | 1 (14.3%) | 1 (2.4%) | 0 (0%) |