Left ventricular systolic function, afterload, contractility, and preload in patients with β thalassaemia major and controls
| Variable | Thalassaemia (n=197) | Controls (n=213) | p Value |
|---|---|---|---|
| Values are mean (SD). | |||
| ESSc, circumferential end systolic stress; ESSm, meridional end systolic stress; FPI, functional preload index; FS, fractional shortening; mVCFc, mean velocity of circumferential shortening corrected by heart rate; PSSc, circumferential peak systolic stress; PSSm, meridional peak systolic stress; SSI, stress shortening index; SVI, stress velocity index. | |||
| FS (%) | 34.7 (5.6) | 37.5 (5.8) | <0.0001 |
| mVCFc (circ/s) | 1.08 (0.19) | 1.21 (0.11) | <0.0001 |
| ESSm (g/cm2) | 55.6 (13.1) | 47.1 (0.4) | <0.0001 |
| PSSm (g/cm2) | 217.9 (35.9) | 209.4 (26.9) | <0.01 |
| ESSc (g/cm2) | 101.5 (20.1) | 92.5 (15.1) | <0.0001 |
| PSSc (g/cm2) | 339.9 (53.3) | 340.2 (38.6) | NS |
| SSI | −0.31 (1.39) | 0.05 (0.75) | <0.0005 |
| SVI | −0.37 (1.40) | 0.15 (0.79) | <0.0001 |
| FPI | 0.05 (0.99) | −0.09 (0.63) | NS |