Left ventricular diastolic function from mitral valve inflow in patients with β thalassaemia major and controls
| Variable | Thalassaemia (n=197) | Controls (n=213) | p Value |
|---|---|---|---|
| Values are mean (SD). | |||
| A, peak A wave; Aa, A wave area; DT, deceleration time; DR, deceleration rate; E, peak E wave; Ea, E wave area; FVI, total flow velocity integral; IVRT, isovolumic relaxation time. | |||
| E (cm/s) | 92.6 (13.6) | 82.6 (13.0) | <0.0001 |
| A (cm/s) | 47.9 (12.7) | 48.1 (10.1) | NS |
| E/A | 2.1 (0.7) | 1.7 (0.5) | <0.0001 |
| DT (s) | 0.167 (0.033) | 0.164 (0.020) | NS |
| DR (cm/s2) | 572 (123) | 515 (125) | <0.0001 |
| IVRT (s) | 0.078 (0.016) | 0.067 (0.007) | <0.0001 |
| FVI (cm) | 19.1 (4.2) | 17.6 (2.2) | <0.0001 |
| E/FVI | 4.9 (0.7) | 4.6 (1.0) | NS |
| Ea (cm) | 13.1 (3.1) | 11.4 (1.9) | <0.0001 |
| Aa (cm) | 4.9 (1.4) | 4.4 (0.9) | <0.0001 |
| Ea/FVI | 0.68 (0.08) | 0.65 (0.06) | <0.0005 |
| Ea/Aa | 2.8 (1.0) | 2.7 (0.8) | NS |