Table 1

Comparison of echocardiographic indices between patients and controls at rest and under dobutamine stress (left hand columns), and comparison of indices between first and second echocardiographic assessment in “normal” and “abnormal” subsets (right hand columns)

Initial assessmentFirst versus second assessments
BaselineDobutamine stressNormal subsetAbnormal subset
VariablesPatients (n=26)Controls (n=20)Patients (n=26)Controls (n=20)First assessment (n=14)Second assessment (n=14)First assessment (n=10)Second assessment (n=10)
Values are mean (SD).
*p<0.05; **p<0.01; ***p<0.001.
EF, ejection fraction; ET, ejection time; FS, fractional shortening; RR, RR interval; Vcfc, rate corrected velocity of circumferential fibre shortening; WS; meridional wall stress.
RR (s)0.80 (0.15)0.79 (0.16)0.78 (0.13)**0.70 (0.13)0.82 (0.16)0.82 (0.14)0.77 (0.15)0.71 (0.14)
ET (s)0.30 (0.03)0.30 (0.03)0.29 (0.05)**0.26 (0.04)0.30 (0.02)0.29 (0.04)0.31 (0.03)0.33 (0.03)
FS (%)0.38 (0.05)0.41 (0.05)0.47 (0.07)***0.54 (0.04)0.38 (0.05)0.35 (0.05)0.35 (0.02)0.32 (0.04)*
EF (%)0.76 (0.06)0.80 (0.06)0.84 (0.08)***0.90 (0.03)0.76 (0.07)0.71 (0.07)0.76 (0.05)0.68 (0.06)***
Vcfc (circ/s)1.11 (0.16)1.23 (0.21)1.42 (0.24)***1.73 (0.26)1.13 (0.16)1.09 (0.15)1.08 (0.17)0.82 (0.11)***
WS (g/cm2)64.34 (14.23)72.67 (11.65)59.89 (22.80)**46.18 (15.57)65.03 (16.38)72.89 (14.68)63.11 (11.90)60.10 (9.62)
Ferritin (μmol/l)4253 (792)4935 (831)5647 (769)6741 (1347)*