Table 3

Retrospective studies of statin treatment in calcific aortic valve stenosis

AuthorYearNumber of patientsRadiological assessmentDegree of regression
EBCT, electron beam computed tomography.
Aronow et al232001180EchoStatin treatment
Change in peak systolic gradient across the aortic valve (−0.370 mm Hg/year)
Novaro et al212001174EchoAortic valve area
Non-statinStatin
0.11 (0.18) cm2/year)0.06 (0.16) cm2/year
Shavelle et al22200265EBCTAortic valve calcium accumulation
Non-statinStatin
32.0%/year10.6%/year
Bellamy et al242001156EchoAortic valve area
Non-statinStatin
−3 (10)%/year−7 (13)%/year