Retrospective studies of statin treatment in calcific aortic valve stenosis
| Author | Year | Number of patients | Radiological assessment | Degree of regression | |
|---|---|---|---|---|---|
| EBCT, electron beam computed tomography. | |||||
| Aronow et al23 | 2001 | 180 | Echo | Statin treatment | |
| Change in peak systolic gradient across the aortic valve (−0.370 mm Hg/year) | |||||
| Novaro et al21 | 2001 | 174 | Echo | Aortic valve area | |
| Non-statin | Statin | ||||
| 0.11 (0.18) cm2/year) | 0.06 (0.16) cm2/year | ||||
| Shavelle et al22 | 2002 | 65 | EBCT | Aortic valve calcium accumulation | |
| Non-statin | Statin | ||||
| 32.0%/year | 10.6%/year | ||||
| Bellamy et al24 | 2001 | 156 | Echo | Aortic valve area | |
| Non-statin | Statin | ||||
| −3 (10)%/year | −7 (13)%/year | ||||