Table 3

Prevalence of the possible HFE genotypes in each subject group

Normal control (n=493)IHD control (n=427)MI survivor (n=828)Normal control v IHD control OR (95% CI)Normal control v MI survivor OR (95% CI)
None of the genotype groups achieved significance.
HFE, haemochromatosis gene.
Wild type268 (54.4%)249 (58.3%)468 (56.5%)1.17 (0.90 to 1.5)1.14 (0.87 to 1.5)
H63D homozygote10 (2.0%)9 (2.1%)23 (2.8%)1.02 (0.41 to 2.6)1.22 (0.51 to 2.9)
H63D heterozygote115 (23.3%)98 (23.0%)198 (23.9%)0.97 (0.71 to 1.3)1.04 (0.76 to 1.4)
Compound heterozygote15 (3.0%)7 (1.6%)31 (3.7%)0.53 (0.21 to 1.3)0.87 (0.42 to 1.8)
C282Y homozygote5 (1.0%)3 (0.7%)7 (0.8%)0.71 (0.17 to 3.0)1.20 (0.23 to 6.2)
C282Y heterozygote80 (16.2%)61 (14.3%)101 (12.2%)0.88 (0.61 to 1.3)0.70 (0.48 to 1.04)