Accuracy (%) for detection of cholesterol and calcification in 1 mm and 2 mm artery sections by Raman spectroscopy
1 mm section | 2 mm section | |||||
---|---|---|---|---|---|---|
Cholesterol | Calcification | β Carotene | Cholesterol | Calcification | β Carotene | |
Cut-off values of 4% (wt/wt), 6% (wt/wt) and 4.0×10−3 au were used for cholesterol, calcification, and β carotene, respectively. The contribution of β carotene was used as an indirect marker for detection of cholesterol (in bold). | ||||||
NPV, negative predictive value; PPV, positive predictive value. | ||||||
Sensitivity | 87 | 81 | 78 | 87 | 78 | 92 |
Specificity | 86 | 95 | 95 | 95 | 97 | 95 |
NPV | 91 | 94 | 97 | 97 | 94 | 95 |
PPV | 80 | 86 | 74 | 80 | 86 | 92 |