Baseline patient characteristics
| Homocysteine concentration | p Value | ||
|---|---|---|---|
| <13.11 μmol/l | ⩾13.11 μmol/l | ||
| *Insulin dependent diabetes mellitus was an exclusion criterion in this trial. | |||
| Data are median (interquartile range) or number (%). | |||
| HDL, high density lipoprotein; LDL, low density lipoprotein. | |||
| Number of patients | 67 | 67 | |
| Mean (SD) age (years) | 57.5 (9.7) | 60.8 (10.6) | 0.07 |
| Male sex | 56 (83.6%) | 53 (79.1%) | 0.51 |
| Any history of smoking | 40 (59.7%) | 47 (70.1%) | 0.21 |
| Current smoking | 2 (3%) | 5 (7.5%) | 0.44 |
| History of diabetes mellitus* | 5 (7.5%) | 2 (3%) | 0.44 |
| History of hypertension | 30 (44.8%) | 30 (44.8%) | 1.0 |
| History of myocardial infarction | 26 (38.8%) | 27 (40.3%) | 0.86 |
| Number of treated lesions per patient | 1 (1–2) | 1 (1–2) | 0.77 |
| Number of patients undergoing directional atherectomy | 5 (7.5%) | 6 (9.0%) | 0.75 |
| Number of patients undergoing rotational atherectomy | 1 (1.5%) | 1 (1.5%) | 1.0 |
| Laboratory findings | |||
| Creatinine (mmol/l) | 0.09 (0.08–0.1) | 0.09 (0.09–0.11) | 0.04 |
| Fibrinogen (g/l) | 3 (2.8–3.5) | 2.9 (2.6–3.4) | 0.2 |
| Cholesterol (mmol/l) | 5.93 (5.25–6.52) | 5.96 (5.33–6.46) | 0.99 |
| HDL cholesterol (mmol/l) | 1.01 (0.85–1.26) | 1.08 (0.86–1.32) | 0.33 |
| LDL cholesterol (mmol/l) | 4.2 (3.5–4.6) | 3.8 (3.45–4.36) | 0.12 |
| Triglyceride (mmol/l) | 1.57 (1.15–2.21) | 1.39 (1.11–2.04) | 0.3 |