Study design and use of reperfusion strategies in studies with interhospital or direct transport of patients to PTCA centre
| Study | Patients | Randomisation | Thrombolysis | PTCA |
|---|---|---|---|---|
| Use of rescue PTCA: in DANAMI-2 study 1.9%, CAPTIM study 26%, PRAGUE-2 study 6.4%. Any PTCA at 30 days: in DANAMI-2 study 16.5%, CAPTIM study 70.4%. | ||||
| PRAGUE-2 | ST ↑ AMI <12 h | In community hospital without PTCA facility to: | Streptokinase | Stents used in 63% |
| Thrombolysis or direct PTCA | ||||
| provided start interhospital transport | ||||
| possible within 30 mins and distance <120 km | ||||
| DANAMI-2 | ST ↑ AMI <12 h | In community hospitalor PTCA centre to: | Accelerated (acc) t-PA | Stents used in 81% |
| Thrombolysis or direct PTCA | Glycoprotein IIb/IIIA blocker in 39% | |||
| if admitted in community hospital: | ||||
| provided transport to PTCA centre completed within 3 hours | ||||
| CAPTIM | ST ↑ AMI <6 h | On site to: | Pre-hospital acc t-PA | Stents used in 81% |
| thrombolysis or direct PTCA + transport to PTCA centre, provided transport duration <1 hour | With rescue PTCA strategy | Glycoprotein IIb/IIIA blocker in 39% | ||