Table 3

Clinical situations where sulfonylurea treatment may be harmful and should therefore be avoided or discontinued

Clinical situationExplanationReference
(1) Acute myocardial infarction
    (a) with acute angioplastyBalloon inflation causes a second period of ischaemia following acute myocardial infarction 41
    (b) without emergency coronary interventionAngioplasty can be necessary at any timeNo studies available
(2) Unstable angina pectorisRepeated or prolonged episodes of myocardial ischaemia 5
(3) Elective angioplastyArtificial induction of repeated or prolonged intracoronary occlusion 42