Baseline characteristics of responders and non-responders
| Responders (n = 20) | Non-responders (n = 10) | p Value | |
|---|---|---|---|
| ANP, atrial natriuretic peptide; BNP, brain natriuretic peptide; LVEF, left ventricular ejection fraction; MR, mitral regurgitation; NS, not significant; NYHA, New York Heart Association; QoL, quality of life; S-L dyssync, difference between septal and lateral peak systolic velocities, indicating dyssynchrony within the left ventricle; 6 min WT, 6 minute walk test. | |||
| Male/female | 15/5 | 8/2 | NS |
| Age (years) | 67 (9) | 60 (16) | NS |
| Aetiology (ischaemic v non-ischaemic) | 8/12 | 5/5 | NS |
| QRS (ms) | 178 (21) | 172 (25) | NS |
| NYHA class | 3.15 (0.4) | 3.0 (0.0) | NS |
| QoL score | 39 (15) | 40 (24) | NS |
| 6 min WT (m) | 26 (106) | 258 (192) | NS |
| LVEF (%) | 22 (7) | 18 (12) | NS |
| MR grade 3–4+ | 6 (30%) | 4 (40%) | NS |
| S-L dyssync (ms) | 90 (20) | 37 (11) | <0.01 |
| N terminal ANP (pmol/l) | 11184 (7339) | 9198 (9711) | NS |
| N terminal BNP (pmol/l) | 1368 (761) | 989 (1269) | NS |