Table 1

Clinical characteristics of the study patients

Nicorandil (n = 30)ISDN (n = 30)p Value
Values are mean (SD) or number (%).
ACE, angiotensin converting enzyme; BP, blood pressure; CK, creatine kinase; HR, heart rate; ISDN, isosorbide dinitrate; MI, myocardial infarction; TIMI, thrombolysis in myocardial infarction.
Mean age (years)60 (9)63 (10)0.38
Male sex23/30 (76.7%)25/30 (83.3%)0.52
Diabetes mellitus5/30 (16.7%)6/30 (20.0%)0.74
Preinfarction angina (<48 h)14/30 (33.3%)12/30 (40.0%)0.80
Mean time from onset to reperfusion (h)5.2 (2.5)5.7 (3.3)0.47
Anterior MI10/30 (33.3%)12/30 (40.0%)0.59
Non-Q MI2/30 (6.6%)1/30 (3.3%)0.59
TIMI grade (0, 1) before angioplasty(26, 4)(25, 5)0.72
TIMI grade (2, 3) after angioplasty(1, 29)(3, 27)0.30
Collateral (grade > 2)3/30 (10.0%)2/30 (6.7%)0.64
ACE inhibitor14/30 (46.7%)15/30 (50.0%)0.79
β Blocker5/30 (16.6%)7/30 (23.3%)0.52
Mean BP (mm Hg)92 (9)89 (7)0.33
Mean HR (beats/min)79 (11)78 (12)0.96
Use of stent1/30 (70.0%)19/30 (63.3%)0.58
Maximum CK concentrations (iu/l)2953 (1950)3595 (2274)0.25