Table 3

Effects of aspirin on markers of haemostatic and inflammatory activity

Placebo (n = 40)ASA (n = 40)p Value
Values are median (interquartile range).
F1+2, plasma prothrombin fragment F1+2; IL, interleukin; MCSF, macrophage colony stimulating factor; TxB2, thromboxane B2; 11-DHTxB2, 11-dehydro-thromboxane B2.
TxB2 (ng/mg creatinine)0.21 (0.15–0.30)0.11 (0.09–0.14)<0.01
11-DHTxB2 (ng/mg creatinine)3.3 (2.3–5.4)1.3 (0.8–3.1)<0.01
F1+2 (nmol/l)1.5 (1.1–2.7)1.2 (1.1–1.8)<0.01
MCSF (pg/ml)991 (459–1476)843 (501–1357)<0.05
IL-6 (pg/ml)3.5 (3.2–4.6)2.9 (2.5–3.4)<0.05