Prevalence of diastolic dysfunction in the overall patient group and subsets at high risk of diastolic dysfunction
| Reference study and patient age range (years) | Prevalence of abnormal diastolic function | ||||
|---|---|---|---|---|---|
| All patients | Hypertension | LVH | Obesity | Ischaemia | |
| LVH, left ventricular hypertrophy. | |||||
| Framingham study20 ⩾ 70 | |||||
| E:A | 2/64 (3.1%) | 1/34 (2.9%) | 1/19 (5.3%) | 0/18 (0%) | 1/26 (3.8%) |
| AFF | 7/63 (11.1%) | 2/34 (5.9%) | 1/18 (5.6%) | 3/17 (18%) | 3/26 (11.5%) |
| Mantero et al18 60–80 | |||||
| E:A | 6/66 (9.1%) | 3/35 (8.6%) | 2/18 (11%) | 1/22 (5%) | 4/30 (13%) |
| AFF | 7/65 (11%) | 1/35 (2.9%) | 1/17 (5.9%) | 5/21 (24%) | 6/34 (18%) |
| IVRT | 24/71 (34%) | 16/38 (42%) | 8/20 (40%) | 6/24 (25%) | 13/33 (39%) |
| DT | 15/68 (22%) | 10/36 (28%) | 4/18 (22%) | 3/23 (13%) | 6/33 (18%) |
| Voutilainen et al21 > 60) | |||||
| AFF | 8/82 (10%) | 4/42 (10%) | 4/22 (18%) | 3/23 (13%) | 5/34 (15%) |
| IVRT | 52/87 (60%) | 25/45 (56%) | 13/25 (52%) | 8/26 (31%) | 22/36 (61%) |
| Klein et al24 > 70 | |||||
| E:A | 2/64 (3.1%) | 0/34 (0%) | 1/19 (5.3%) | 0/18 (0%) | 0/26 (0%) |
| IVRT | 27/67 (40%) | 16/36 (44%) | 9/21 (43%) | 7/19 (37%) | 11/27 (41%) |
| DT | 8/65 (12%) | 7/34 (21%) | 1/19 (53%) | 2/18 (11%) | 3/27 (11%) |
| Cohen et al9 ⩾ 50 | |||||
| E:A | 9/91 (9.9%) | 4/44 (9.1%) | 3/25 (12%) | 1/28 (4%) | 3/34 (9%) |
| IVRT | 20/95 (21%) | 10/47 (21%) | 6/27 (22%) | 6/30 (19%) | 8/37 (22%) |
| DT | 11/93 (12%) | 8/45 (18%) | 2/27 (7%) | 2/29 (6%) | 5/37 (14%) |
| Spirito et al19 50–74 | |||||
| E:A | 1/54 (2%) | 0/26 (0%) | 0/14 (0%) | 0/22 (0%) | 0/19 (0%) |
| IVRT | 21/60 (35%) | 11/28 (39%) | 5/15 (33%) | 9/24 (36%) | 8/22 (36%) |
| DT | 11/56 (20%) | 8/27 (30%) | 2/14 (14%) | 4/23 (17%) | 5/21 (24%) |
| European Study Group on Diastolic Heart Failure11 > 50 | |||||
| IVRT | 45/95 (47%) | 18/47 (38%) | 14/27 (52%) | 15/30 (50%) | 16/37 (43%) |
| E:A+DT | 3/91 (3%) | 2/45 (4%) | 1/25 (4%) | 0/29 (0%) | 1/35 (3%) |