Variable | Placebo (n = 14) | Pinacidil (n = 14) | Glibenclamide (n = 10) | ||
---|---|---|---|---|---|
Values are mean (SD). | |||||
*p<0.05 v baseline. | |||||
Borg score, scoring system for estimating anginal pain; STmax, the peak amplitude of ST segment deviation in the most deviating lead; STsum, the total magnitude of ST segment deviation average over 12 lead for the ECG with STmax; %ΔSTmax, %ΔSTsum, percent change compared with baseline. | |||||
Baseline | STmax (μV) | 104 (65) | 130 (59) | 134 (52) | NS |
STsum (μV) | 36 (16) | 39 (18) | 47 (28) | NS | |
Borg sore | 0 | 0 | 0 | NS | |
NS | |||||
Inflation 1 | STmax (μV) | 432 (265)* | 451 (335)* | 327 (162)* | NS |
%ΔSTmax | 674 (1379) | 394 (557) | 176 (163) | NS | |
STsum (μV) | 125 (66)* | 139 (86)* | 114 (45)* | NS | |
%ΔSTsum | 303 (236) | 338 (306) | 243 (258) | NS | |
Borg score | 4(2)* | 4 (2)* | 3 (3)* | NS | |
Reperfusion 1 | STmax (μV) | 83 (65) | 94 (45) | 83 (52) | NS |
STsum (μV) | 27 (16) | 35 (11) | 43 (19) | NS | |
NS | |||||
Inflation 2 | STmax | 389 (258)* | 383 (217)* | 339 (214)* | NS |
%ΔSTmax | 555 (l019) | 331 (437) | 189 (214) | NS | |
STsum | 122 (61)* | 111 (46)* | 123 (63)* | NS | |
%ΔSTsum | 286 (199) | 269 (271) | 248 (258) | NS | |
Borg score | 4(3)* | 4 (2)* | 3 (2)* | NS | |
Reperfusion 2 | STmax (μV) | 91 (62) | 86 (37) | 84 (52) | NS |
STsum (μV) | 31 (15) | 34 (14) | 47(25) | NS | |
NS | |||||
Inflation 3 | STmax (μV) | 416 (287)* | 350 (199)* | 310 (186)* | NS |
%ΔSTmax | 581 (1111) | 297 (359) | 162 (193) | NS | |
STsum (μV) | 118 (65)* | 110 (34)* | 107 (52)* | NS | |
%ΔSTsum | 282 (219) | 275 (290) | 200 (232) | NS | |
Borg score | 4 (3)* | 4 (2)* | 2 (2)* | NS | |
Reperfusion 3 | STmax (μV) | 84 (69) | 91 (35) | 89(61) | NS |
STsum (μV) | 31 (15) | 33 (9) | 47(23) | NS |